{"result":[{"lastName":"McAdams","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Developmental Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4403&type=small&showNoImage","displayName":"Harley McAdams","firstName":"Harley","href":"http://coe.stanford.edu/profiles/Harley_McAdams","researchInterest":"Experimental and theoretical analysis and modeling of genetic regulatory circuits, particularly bacterial regulation and with emphasis on global regulation of Caulobacter crescentus. Bioinformatic analysis of bacterial genomes, of microarray expression patterns, and cross-species genomic analysis. Techniques: gene expression microarrays, fluorescent microscopy, electron microscopy, genetics, molecular biology"},{"lastName":"Shapiro","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4316&type=small&showNoImage","displayName":"Lucy Shapiro","firstName":"Lucille","href":"http://coe.stanford.edu/profiles/Lucille_Shapiro","researchInterest":"A basic question in developmental biology involves the mechanisms used to generate the three-dimensional organization of a cell from a one-dimensional genetic code. Our goal is to define these mechanisms using both molecular genetics and biochemistry."},{"lastName":"Moerner","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=8121&type=small&showNoImage","displayName":"W. E. Moerner","firstName":"W","href":"http://coe.stanford.edu/profiles/W_Moerner","researchInterest":"Physical chemistry/chemical physics: single-molecule imaging and spectroscopy in condensed phases; superresolution imaging of biomolecules in cells; fluorophores for cellular imaging; single-molecule biophysics; nanophotonics to produce enhanced optical fields; trapping single molecules in solution"},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Assistant Professor,Microbiology & Immunology"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=10429&type=small&showNoImage","displayName":"KC Huang","firstName":"Kerwyn","href":"http://coe.stanford.edu/profiles/Kerwyn_Huang","researchInterest":""},{"lastName":"Ptacin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=9825&type=small&showNoImage","displayName":"Jerod Ptacin","firstName":"Jerod","href":"http://coe.stanford.edu/profiles/Jerod_Ptacin","researchInterest":""},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4190&type=small&showNoImage","displayName":"Oleg Jardetzky","firstName":"Oleg","href":"http://coe.stanford.edu/profiles/Oleg_Jardetzky","researchInterest":"Structure, dynamics and function of proteins involved in transport and regulatory processes; high resolution nuclear magnetic resonance studies of conformational transitions and protein folding; study of the mechanism of action of the trp-repressor, ankyrin-domain proteins and the development of programs to calculate protein solution structure"},{"lastName":"Yanofsky","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","displayName":"Charles Yanofsky","firstName":"Charles","href":"http://coe.stanford.edu/profiles/Charles_Yanofsky","researchInterest":""},{"lastName":"Wang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Civil and Environmental Engineering"}],"primaryAppointment":"Postdoctoral Research fellow, Civil and Environmental Engineering","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=21241&type=small&showNoImage","displayName":"Dan Wang","firstName":"Dan","href":"http://coe.stanford.edu/profiles/Dan_Wang","researchInterest":""},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://coe.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Tan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=14657&type=small&showNoImage","displayName":"Meng How Tan","firstName":"Meng How","href":"http://coe.stanford.edu/profiles/Meng How_Tan","researchInterest":""},{"lastName":"Smith","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Radiation Oncology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Radiation Oncology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=7014&type=small&showNoImage","displayName":"Kendric C. Smith","firstName":"Kendric","href":"http://coe.stanford.edu/profiles/Kendric_Smith","researchInterest":"The photochemistry and radiation chemistry of DNA, the genetic control and biochemical bases of the multiple pathways of DNA repair, and the roles of DNA repair processes in radiation and spontaneous mutagenesis. Over 190 papers have been published on these and related topics."},{"lastName":"Campbell","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=6212&type=small&showNoImage","displayName":"Allan Campbell","firstName":"Allan","href":"http://coe.stanford.edu/profiles/Allan_Campbell","researchInterest":""},{"lastName":"Falkow","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Microbiology & Immunology"},{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Professor Emeritus,Microbiology & Immunology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4488&type=small&showNoImage","displayName":"Stanley Falkow","firstName":"Stanley","href":"http://coe.stanford.edu/profiles/Stanley_Falkow","researchInterest":"Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.  \r\n\r\nPlease contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu)."},{"lastName":"Storek","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=34606&type=small&showNoImage","displayName":"Kelly Colvin Storek","firstName":"Kelly","href":"http://coe.stanford.edu/profiles/Kelly_Storek","researchInterest":""},{"lastName":"Monack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Microbiology & Immunology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=8324&type=small&showNoImage","displayName":"Denise M. Monack","firstName":"Denise","href":"http://coe.stanford.edu/profiles/Denise_Monack","researchInterest":"The primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis.  We use two model systems, Salmonella typhimurium and Francisella tularensis, to study the complex host-pathogen interactions.  Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response and how F. tularensis, a stealth invader, can cause a rapid, lethal infection."},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://coe.stanford.edu/profiles/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://coe.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Vasquez","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=12553&type=small&showNoImage","displayName":"Valeria Vasquez","firstName":"Valeria","href":"http://coe.stanford.edu/profiles/Valeria_Vasquez","researchInterest":""},{"lastName":"Kornberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4308&type=small&showNoImage","displayName":"Roger Kornberg","firstName":"Roger","href":"http://coe.stanford.edu/profiles/Roger_Kornberg","researchInterest":"We study the regulation of transcription, the first step in gene expression. The main lines of our work are 1) reconstitution of the process with more than 50 pure proteins and mechanistic analysis, 2) structure determination of the 50 protein complex at atomic resolution, and 3) studies of chromatin remodelling, required for transcription of the DNA template in living cells"},{"lastName":"Theriot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4432&type=small&showNoImage","displayName":"Julie Theriot","firstName":"Julie","href":"http://coe.stanford.edu/profiles/Julie_Theriot","researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis."},{"lastName":"Ohlson","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=9289&type=small&showNoImage","displayName":"Maikke Ohlson","firstName":"Maikke","href":"http://coe.stanford.edu/profiles/Maikke_Ohlson","researchInterest":""},{"lastName":"Sathiyamoorthy","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=21151&type=small&showNoImage","displayName":"Karthik Sathiyamoorthy","firstName":"Karthik","href":"http://coe.stanford.edu/profiles/Karthik_Sathiyamoorthy","researchInterest":""},{"lastName":"Covert","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=7986&type=small&showNoImage","displayName":"Markus Covert","firstName":"Markus","href":"http://coe.stanford.edu/profiles/Markus_Covert","researchInterest":"Our focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors."},{"lastName":"Chien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://coe.stanford.edu/profiles/viewImage?facultyId=4121&type=small&showNoImage","displayName":"Yueh-hsiu Chien","firstName":"Yueh-Hsiu","href":"http://coe.stanford.edu/profiles/Yueh-Hsiu_Chien","researchInterest":"Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses."}]}